Bicyclobutanes: from curiosities to versatile reagents and covalent warheads-Reference-Cited by-同舟云学术

Bicyclobutanes: from curiosities to versatile reagents and covalent warheads

Published:2022 Issue:40 Volume:13 Page:11721-11737
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kelly Christopher B.¹^ORCID,Milligan John A.²^ORCID,Tilley Leon J.³^ORCID,Sodano Taylor M.⁴^ORCID

Affiliation:

1. Discovery Process Research, Janssen Research & Development LLC, 1400 McKean Road, Spring House, PA 19477, USA

2. Department of Biological and Chemical Sciences, College of Life Sciences, Thomas Jefferson University, 4201 Henry Avenue, Philadelphia, PA 19144, USA

3. Department of Chemistry, Stonehill College, 320 Washington Street, Easton, MA 02357, USA

4. Therapeutics Discovery, Janssen Research & Development LLC, 1400 McKean Road, Spring House, PA 19477, USA

Abstract

A flurry of reports for preparing, functionalizing, and using bicyclo[1.1.0]butanes (BCBs) have positioned them to be powerful synthons with numerous applications. This review discusses the recent developments regarding this strained carbocycle.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC03948F

Reference154 articles.

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3. Straining to react

4. Recent advances in the chemistry of bicyclo- and 1-azabicyclo[1.1.0]butanes

5. Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes

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