Human mesenchymal stem cells promote survival and prevent intestinal damage in a mouse model of radiation injury

Author:

Guo Meng-Zheng12345,Gong Wei12345,Zhang Hong-Wei6789,Wang Yan12345,Du Li-Qing12345,Xu Chang12345,Wang Qin12345,Zhao Hui101112139,Liu Qiang12345,Fan Fei-Yue12345

Affiliation:

1. Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine

2. Department of Radiobiology

3. Institute of Radiation Medicine of Chinese Academy of Medical Science

4. Peking Union Medical College

5. Tianjin 300192

6. Tangshan People’s Hospital

7. North China University of Science and Technology

8. Tangshan 063001

9. China

10. Tianjin Key Laboratory of Food and Biotechnology

11. School of Biotechnology and Food Science

12. Tianjin University of Commerce

13. Tianjin 300134

Abstract

In the present study, we examined the protective effects of human umbilical cord mesenchymal stem cells (hMSCs) against intestinal stem cell (ISC) death and intestinal damage in a mouse model of radiation injury.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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