Convenient synthesis of functionalized spiro[indoline-3,2′-pyrrolizines] or spiro[indoline-3,3′-pyrrolidines] via multicomponent reactions

Abstract

Multicomponent reactions of α-amino acids, dialkyl acetylenedicarboxylates and 3-methyleneoxindoles afforded diverse functionalized spiro[indoline-3,2′-pyrrolizines], spiro[indoline-3,3′-pyrrolidines] and spiro[indoline-3,6′-pyrrolo[1,2-c]thiazoles].