Photoactivatable dihydroalkaloids for cancer cell imaging and chemotherapy with high spatiotemporal resolution

Author:

Ling Xia12345,Huang Letao67895,Li Youzhen12345,Wan Qing67895,Wang Zhiming67895ORCID,Qin Anjun67895ORCID,Gao Meng12345ORCID,Tang Ben Zhong67895ORCID

Affiliation:

1. National Engineering Research Center for Tissue Restoration and Reconstruction

2. Key Laboratory of Biomedical Engineering of Guangdong Province

3. Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education

4. Innovation Center for Tissue Restoration and Reconstruction

5. South China University of Technology

6. AIE Institute

7. Center for Aggregation-Induced Emission

8. Key Laboratory of Luminescence from Molecular Aggregates of Guangdong Province

9. State Key Laboratory of Luminescent Materials and Devices

Abstract

A photoactivatable strategy is proposed for precise cancer therapy based on photooxidative dehydrogenation reaction, which is demonstrated with the natural dihydroalkaloids of DHCHE and DHSAN as an example.

Funder

National Natural Science Foundation of China

Pearl River S and T Nova Program of Guangzhou

Natural Science Foundation of Guangdong Province

Fundamental Research Funds for the Central Universities

Innovation and Technology Commission - Hong Kong

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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