A poly-δ-decalactone (PDL) based nanoemulgel for topical delivery of ketoconazole and eugenol against <i>Candida albicans</i>-Reference-Cited by-同舟云学术

A poly-δ-decalactone (PDL) based nanoemulgel for topical delivery of ketoconazole and eugenol against Candida albicans

Published:2024 Issue: Volume: Page:
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Dubey Prashant¹,Kumar Ankaj¹^ORCID,Vaiphei Klaudi K.¹^ORCID,Basrani Sargun²,Jadhav Ashwini²,Wilen Carl-Eric³,Rosenholm Jessica M.⁴,Bansal Kuldeep K.³⁴^ORCID,Chakravarti Rudra⁵,Ghosh Dipanjan⁵^ORCID,Gulbake Arvind¹^ORCID

Affiliation:

1. Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Guwahati, Assam, 781101, India

2. Department of Medical Biotechnology, CIR, D.Y. Patil Education Society, Institution Deemed to be University, Kolhapur, India

3. Laboratory of Molecular Science and Engineering, Åbo Akademi University, Aurum, Henrikinkatu 2, 20500 Turku, Finland

4. Pharmaceutical Sciences Laboratory, Faculty of Science and Engineering, Åbo Akademi University, Turku 20520, Finland

5. Department of Natural Products, National Institute of Pharmaceutical Education and Research, Kolkata, India

Abstract

The renewable PDL (poly-δ-decalactone) and mPEG-b-PDL (methoxy-poly(ethylene glycol)-b-PDL) based nanoemulsion (NE) bearing ketoconazole (KTZ) and eugenol (EUG) were developed and finally, KTZ–EUG–NE-based gel were investigated for topical delivery against Candida albicans.

Funder

Stiftelsen för Åbo Akademi

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NA/D4NA00176A

Reference59 articles.

1. Antifungal Cationic Nanoemulsion Ferrying Miconazole Nitrate with Synergism to Control Fungal Infections: In Vitro, Ex Vivo, and In Vivo Evaluations

2. Preparation and Optimization of Itraconazole Transferosomes-Loaded HPMC Hydrogel for Enhancing Its Antifungal Activity: 2^3 Full Factorial Design

3. Tackling the emerging threat of antifungal resistance to human health

4. Enhanced effect in combination of curcumin- and ketoconazole-loaded methoxy poly (ethylene glycol)-poly (ε-caprolactone) micelles

5. A.Kumar , D.Panwar , V.Bhavana , P.Thakor , P. K.Singh and N. K.Mehra , Lipid-Based Nanomaterials: A Brief Note on Composition, Development, and Drug Delivery Applications , in Nanomaterial-Based Drug Delivery Systems: Therapeutic and Theranostic Applications , ed. C. V. Pardeshi , Springer International Publishing , Cham , 2023 , pp. 65–98