Mannobioside biomimetics that trigger DC-SIGN binding selectivity-Reference-Cited by-同舟云学术

Mannobioside biomimetics that trigger DC-SIGN binding selectivity

Published:2022 Issue:86 Volume:58 Page:12086-12089
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Herrera-González Irene¹,Thépaut Michel²,Sánchez-Fernández Elena M.¹,di Maio Antonio³^ORCID,Vivès Corinne²,Rojo Javier³^ORCID,García Fernández José M.³^ORCID,Fieschi Franck²^ORCID,Nieto Pedro M.³^ORCID,Ortiz Mellet Carmen¹^ORCID

Affiliation:

1. Department of Organic Chemistry, Faculty of Chemistry, University of Seville, C/Profesor García González 1, Seville 41012, Spain

2. Université Grenoble Alpes, CNRS, CEA, Institut de Biologie Structurale, Grenoble 38044, France

3. Instituto de Investigaciones Químicas (IIQ), CSIC – Universidad de Sevilla, Américo Vespucio 49, Sevilla 41092, Spain

Abstract

Oligosaccharide biomimetics featuring sp2-iminosugar motifs enable selective C-type lectin recognition, as exemplified here for DC-SIGN vs langerin, offering new opportunities for immunomodulation.

Funder

European Science Foundation

Agencia Estatal de Investigación

European Regional Development Fund

Agence Nationale de la Recherche

Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía

Junta de Andalucía

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC04478A

Reference36 articles.

1. Molecular Recognition in C‐Type Lectins: The Cases of DC‐SIGN, Langerin, MGL, and L‐Sectin

2. C-Type Lectin Receptors in Host Defense Against Bacterial Pathogens

3. Medicinal chemistry of the myeloid C-type lectin receptors Mincle, Langerin, and DC-SIGN

4. DC-SIGN: escape mechanism for pathogens

5. DC-SIGN-Mediated Internalization of HIV Is Required for Trans-Enhancement of T Cell Infection

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