Synthesis of unsymmetrical 1,3-substituted-1,3-dihydro-benzimidazolones <i>via</i> copper-catalyzed C–N coupling under visible light-Reference-Cited by-同舟云学术

Synthesis of unsymmetrical 1,3-substituted-1,3-dihydro-benzimidazolones via copper-catalyzed C–N coupling under visible light

Published:2022 Issue:26 Volume:46 Page:12465-12469
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Liu Jianjun¹,Zuo Shengli¹,Huang Jieying¹,Zhang Fan¹,Zuo Ang²³^ORCID

Affiliation:

1. State Key Laboratory of Chemical Resource Engineering, Department of Applied Chemistry, College of Chemistry, Beijing University of Chemical Technology, Beijing 100124, China

2. Department of Pharmaceutical Sciences, College of Pharmacy and UICentre (Drug Discovery at UIC), University of Illinois at Chicago, Chicago, Illinois 60612, USA

3. SynChem, Inc., 1400 Chase Avenue, Elk Grove Village, Illinois 60007, USA

Abstract

Although photoinduced copper catalysis for carbon–nitrogen (C–N) amine bond formation with alkyl/aryl halides has been developed, the potential of copper photocatalysis for the synthesis of 1,3-substituted benzimidazolones remains mostly unexplored.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ02054H

Reference35 articles.

1. Process Development of a CRF1 Receptor Antagonist Based on the Selective Chlorination of a Benzimidazolone via Chlorine Migration

2. Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks

3. Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists

4. N-Aryl-benzimidazolones as novel small molecule HSP90 inhibitors

5. Potent benzimidazolone based human β3-adrenergic receptor agonists

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