Dual functionalized amino poly(glycerol methacrylate) with guanidine and Schiff-base linked imidazole for enhanced gene transfection and minimized cytotoxicity-Reference-Cited by-同舟云学术

Dual functionalized amino poly(glycerol methacrylate) with guanidine and Schiff-base linked imidazole for enhanced gene transfection and minimized cytotoxicity

Published:2015 Issue:34 Volume:3 Page:6911-6918
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Guo Pan¹²³⁴⁵,Gu Wenxing¹²³⁴⁵,Chen Qixian⁶⁷⁸⁹,Lu Hongguang¹²³⁴⁵,Han Xiongqi¹²³⁴⁵,Li Wei¹²³⁴⁵,Gao Hui¹²³⁴⁵

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion

3. Tianjin University of Technology

4. Tianjin

5. China

6. Department of Chemistry

7. Massachusetts Institute of Technology

8. Cambridge

9. USA

Abstract

Guanidine and Schiff-base linked imidazole dual functionalized poly(glycerol methacrylate) (IGEP) leads to minimized cytotoxicity and better transfection efficacy than PEI_25K.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB01291K

Reference44 articles.

1. Hydrophobic modifications of cationic polymers for gene delivery

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3. Dual-targeted polyplexes: One step towards a synthetic virus for cancer gene therapy

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5. Adenoviral Gene Delivery from Multilayered Polyelectrolyte Architectures

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