Efficient construction of a stable linear gene based on a TNA loop modified primer pair for gene delivery-Reference-Cited by-同舟云学术

Efficient construction of a stable linear gene based on a TNA loop modified primer pair for gene delivery

Published:2020 Issue:68 Volume:56 Page:9894-9897
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Lu Xuehe¹²³⁴⁵,Wu Xiaohui⁶⁷⁸⁹⁵,Wu Tiantian⁶⁷⁸⁹⁵,Han Lin¹²³⁴⁵,Liu Jianbing⁶⁷⁸⁹⁵,Ding Baoquan¹²³⁴⁵^ORCID

Affiliation:

1. School of Materials Science and Engineering

2. Henan Institute of Advanced Technology

3. Zhengzhou University

4. Zhengzhou

5. China

6. CAS Key Laboratory of Nanosystem and Hierarchical Fabrication

7. CAS Center for Excellence in Nanoscience

8. National Center for Nanoscience and Technology

9. Beijing

Abstract

A TNA loop modified primer pair was designed to construct a stable terminal-closed linear gene, which can be used as an efficient gene expression system in eukaryotic cells.

Funder

National Natural Science Foundation of China

K. C. Wong Education Foundation

National Basic Research Program of China

Beijing Municipal Science and Technology Commission

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC04356G

Reference49 articles.

1. Gene therapy returns to centre stage

2. The promises and pitfalls of RNA-interference-based therapeutics

3. Therapeutic genome editing: prospects and challenges

4. Antisense oligonucleotides: a new therapeutic principle

5. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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