Crystalline pyrazine-2-amidoxime isolated by diffusion method and its structural and behavioral analysis in the context of crystal engineering and microbiological activity

Author:

Chylewska Agnieszka1234,Ogryzek Małgorzata1234,Głębocka Angelika1234,Sikorski Artur1234,Turecka Katarzyna564,Raczyńska Ewa. D.7894,Makowski Mariusz1234

Affiliation:

1. Faculty of Chemistry

2. University of Gdansk

3. 80-308 Gdansk

4. Poland

5. Faculty of Pharmacy with Subfaculty of Laboratory Medicine

6. 80-416 Gdansk

7. Department of Chemistry

8. Warsaw University of Life Sciences

9. 02-776 Warszawa

Abstract

The physicochemical characterizations of PAOX were obtained both in solid-state and solution, and its two anti-conformers were observed in the X-ray. Its antimicrobial properties were tested against reference strains of bacteria and yeast.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference58 articles.

1. K. D. Tripathi , Essentials of medical pharmacology, Jaypee brother’s medical publishers, New Delhi, 6th edn, 2008, pp. 39–50

2. S. S. Kadam , K. R.Mahadik and K. G.Bothara, Principles of medicinal chemistry, Nirali Prakashan, 6th edn., 1999, pp. 169–175

3. Synthesis and Biological Activity of Some New Pyrazolo[3,4-b]Pyrazines

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