Tumor acidity-induced surface charge modulation in covalent nanonetworks for activated cellular uptake: targeted delivery of anticancer drugs and selective cancer cell death-Reference-Cited by-同舟云学术

Tumor acidity-induced surface charge modulation in covalent nanonetworks for activated cellular uptake: targeted delivery of anticancer drugs and selective cancer cell death

Published:2023 Issue:16 Volume:11 Page:5549-5559
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Santra Subrata¹,Das Shreya²,Sengupta Arunima²,Molla Mijanur Rahaman¹^ORCID

Affiliation:

1. Department of Chemistry, University of Calcutta, 92 A. P. C. Road, Kolkata-700009, India

2. Department of Life Science & Biotechnology, Jadavpur University, Kolkata-700032, India

Abstract

A β-thioester and tertiary amine based nanonetwork endowed with dual pH responsive features (tumor acidity induced surface charge modulation and endosomal pH triggered degradation) has been designed for targeted chemotherapeutic applications.

Funder

Council of Scientific and Industrial Research, India

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00491K

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1. Supramolecular Chemistry of p-Sulfonatocalix[n]arenes and Its Biological Applications

2. Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities