Synthesis and in vitro antibacterial activity of novel fluoroalkyl-substituted pyrazolyl oxazolidinones-Reference-Cited by-同舟云学术

Synthesis and in vitro antibacterial activity of novel fluoroalkyl-substituted pyrazolyl oxazolidinones

Published:2015 Issue:90 Volume:5 Page:73660-73669
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yan Lili¹²³⁴⁵,Wu Jingjing¹²³⁴⁵,Chen Heng¹²³⁴⁵,Zhang Shaowu¹²³⁴⁵,Wang Zhi¹²³⁴⁵,Wang Hui⁶⁷⁸⁹⁵,Wu Fanhong¹²³⁴⁵

Affiliation:

1. Department of Pharmaceutical Engineering

2. School of Chemical and Environmental Engineering

3. Shanghai Institute of Technology (SIT)

4. Shanghai 201418

5. China

6. Department of Microbiology

7. School of Life Science and Technology

8. China Pharmaceutical University

9. Nanjing 210009

Abstract

A series of novel fluoroalkyl-substituted pyrazole bearing oxazolidinone derivatives were synthesized and evaluated for their antibacterial activity against six Gram-positive bacterial pathogens. Most have good antibacterial activity, three being comparable to linezolid.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA11782H

Reference27 articles.

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5. Linezolid - a review of the first oxazolidinone

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