Synthesis of oxetane and azetidine ethers as ester isosteres by Brønsted acid catalysed alkylation of alcohols with 3-aryl-oxetanols and 3-aryl-azetidinols-Reference-Cited by-同舟云学术

Synthesis of oxetane and azetidine ethers as ester isosteres by Brønsted acid catalysed alkylation of alcohols with 3-aryl-oxetanols and 3-aryl-azetidinols

Published:2023 Issue:27 Volume:21 Page:5553-5559
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Saejong Peerawat¹^ORCID,Rojas Juan J.¹^ORCID,Denis Camille¹²,White Andrew J. P.¹^ORCID,Voisin-Chiret Anne Sophie²^ORCID,Choi Chulho³^ORCID,Bull James A.¹^ORCID

Affiliation:

1. Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, UK

2. Normandie Univ, UNICAEN, CERMN, 14000 Caen, France

3. Pfizer Global Research and Development, 445 Eastern Point Rd., Groton, CT 06340, USA

Abstract

3-Aryloxetan-3-ols and 3-arylazetidin-3-ols can be selectively activated to form carbocations and allow reaction with alcohols to form ethers with the 4-membered heterocycles.

Funder

Imperial College London

Royal Society

Institute for the Promotion of Teaching Science and Technology

Pfizer

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00731F

Reference54 articles.