Potentiality of zinc phosphate@hydroxyapatite/β-cyclodextrin composites for carrying cisplatin: loading, release and cytotoxicity

Author:

Bin Jumah May N.1,Al Othman Sarah I.1,Alomari Awatif Abdulaziz1,Allam Ahmed A.23,Abukhadra Mostafa R.45ORCID

Affiliation:

1. Biology Department, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia

2. Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt

3. Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Kingdom of Saudi Arabia

4. Geology Department, Faculty of Science, Beni-Suef University, Beni-Suef, 65211, Egypt

5. Materials Technologies and their Applications Lab, Geology Department, Faculty of Science, Beni-Suef University, Beni-Suef City, Egypt

Abstract

A zinc phosphate/hydroxyapatite composite (ZP/HAP) with a core–shell nano-rod morphology and its functionalized derivative with β-cyclodextrin (β-CD) were evaluated as potential carriers of the cisplatin drug (CPN).

Funder

Deanship of Scientific Research, Princess Nourah Bint Abdulrahman University

Publisher

Royal Society of Chemistry (RSC)

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