Aminoglycoside-mimicking carbonized polymer dots for bacteremia treatment

Author:

Chiou Yi-Ru1,Lin Chin-Jung2,Harroun Scott G.3,Chen Yi-Ru2,Chang Lung4,Wu An-Tai5,Chang Fu-Chieh46,Lin Yang-Wei5ORCID,Lin Han-Jia2,Anand Anisha2,Unnikrishnan Binesh2,Nain Amit7,Huang Chih-Ching289ORCID

Affiliation:

1. Graduate Institute of Photonics, National Changhua University of Education, Changhua 50058, Taiwan

2. Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 202301, Taiwan

3. Department of Chemistry, Université de Montréal, Montréal, Québec H3C 3J7, Canada

4. Department of Pediatrics, Mackay Memorial Hospital and Mackay, Junior College of Medicine Nursing and Management, Taipei 10449, Taiwan

5. Department of Chemistry, National Changhua University of Education, Changhua 50058, Taiwan

6. Nursing and Management, Mackay Junior College of Medicine, Taipei 11260, Taiwan

7. Department of Chemistry, National Taiwan University, Taipei 10617, Taiwan

8. Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung 202301, Taiwan

9. School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan

Abstract

Aminoglycoside-mimicking carbonized polymer dots (CPDs) for bacteremia treatment by blocking the synthesis of bacterial proteins and disrupting bacterial membranes.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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