Scalable mesenchymal stem cell enrichment from bone marrow aspirate using deterministic lateral displacement (DLD) microfluidic sorting-Reference-Cited by-同舟云学术

Scalable mesenchymal stem cell enrichment from bone marrow aspirate using deterministic lateral displacement (DLD) microfluidic sorting

Published:2023 Issue:19 Volume:23 Page:4313-4323
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Tan Kwan Zen Nicholas¹²^ORCID,Zeming Kerwin Kwek¹^ORCID,Teo Kim Leng³,Loberas Mavis⁴⁵,Lee Jialing³,Goh Chin Ren¹,Yang Da Hou¹,Oh Steve³,Hui Hoi Po James⁴⁵,Cool Simon M.⁵⁶⁷^ORCID,Hou Han Wei¹²⁸^ORCID,Han Jongyoon¹⁹¹⁰^ORCID

Affiliation:

1. Critical Analytics for Manufacturing of Personalized Medicine, Singapore-MIT Alliance for Research and Technology (SMART), 138602, Singapore

2. School of Mechanical and Aerospace Engineering, Nanyang Technological University, 639798, Singapore

3. Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 138668, Singapore

4. NUS Tissue Engineering Program, Life Sciences Institute, National University of Singapore, 117510, Singapore

5. Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, 119288, Singapore

6. Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), 138668, Singapore

7. School of Chemical Engineering, University of Queensland, Brisbane, 4072, Australia

8. Lee Kong Chian School of Medicine, Nanyang Technological University, 308232, Singapore

9. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA

10. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, USA

Abstract

MSCs are enriched twice more efficiently with 10-fold shorten processing time from undiluted human bone marrow aspirate.

Funder

National Research Foundation Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00379E

Reference68 articles.

1. Regenerative medicine: Current therapies and future directions

2. Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy

3. Multilineage Potential of Adult Human Mesenchymal Stem Cells

4. Mesenchymal Stem Cell Transplantation Attenuates Brain Injury After Neonatal Stroke

5. Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy

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