An attenuated total reflection (ATR) and Raman spectroscopic investigation into the effects of chloroquine on Plasmodium falciparum-infected red blood cells
Author:
Affiliation:
1. Faculty of Chemistry
2. Kraków
3. Poland
4. Monash Institute of Pharmaceutical Sciences
5. Monash University
6. Parkville
7. Australia
8. Department of Microbiology
9. Clayton
10. Centre for Biospectroscopy and School of Chemistry
Abstract
Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) and Raman spectroscopy were used to compare chloroquine (CQ)-treated and untreated cultured Plasmodium falciparum-infected human red blood cells (iRBCs).
Funder
Australian Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/AN/C4AN01904K
Reference27 articles.
1. CHLOROQUINE-RESISTANT FALCIPARUM MALARIA IN THAILAND
2. Chloroquine: Mechanism of drug action and resistance in plasmodium falciparum
3. A perspective on antimalarial action: Effects of weak bases on Plasmodium falciparum
4. Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum
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