A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats-Reference-Cited by-同舟云学术

A high-throughput bioanalytical assay to support pharmacokinetic interaction study of oxycodone and diazepam in Sprague Dawley rats

Published:2020 Issue:2 Volume:10 Page:886-896
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pilli Nageswara R.¹²³⁴⁵^ORCID,Narayanasamy Suresh¹²³⁴⁵,Xu Lin¹²³⁴⁵,Chockalingam Ashok¹²³⁴⁵,Shea Katherine I.¹²³⁴⁵,Stewart Sharron¹²³⁴⁵,Rouse Rodney¹²³⁴⁵,Patel Vikram¹²³⁴⁵,Matta Murali K.¹²³⁴⁵^ORCID

Affiliation:

1. Division of Applied Regulatory Science

2. Office of Clinical Pharmacology

3. Office of Translational Sciences

4. Center for Drug Evaluation and Research

5. Food and Drug Administration

Abstract

A high-throughput bioanalytical method for the simulataneous determination of oxycodone and diazepam to support the evaluation of respiratory depression in rats upon co-administration of oxycodone and diazepam.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA05785D

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