Exposure biomarker profiles of polycyclic aromatic hydrocarbons based on a rat model using a versatile analytical framework

Author:

Jia Xiaoqian12,Long Manman12,Pang Yiming3,An Hang12,Jin Yu4,Jiang Jianjun5,Li Zhiwen12,Wang Bin1267ORCID

Affiliation:

1. Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China

2. Institute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, National Health Commission of the People's Republic of China, Beijing 100191, China

3. Department of Epidemiology, School of Public Health and Management, Binzhou Medical University, Yantai 264003, China

4. State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, Beijing 100142, China

5. Department of Toxicology, School of Public Health, Peking University, Beijing 100191, China

6. Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing 100191, China

7. College of Urban and Environmental Sciences, Peking University, Beijing 100871, China

Abstract

A comprehensive analytical framework was developed to select appropriate exposure biomarkers of polycyclic aromatic hydrocarbons (PAHs).

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

National Key Research and Development Program of China

Major Science and Technology Projects in Yunnan Province

Publisher

Royal Society of Chemistry (RSC)

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