Identification of α-glucosidase inhibitors from cyclocarya paliurus tea leaves using UF-UPLC-Q/TOF-MS/MS and molecular docking-Reference-Cited by-同舟云学术

Identification of α-glucosidase inhibitors from cyclocarya paliurus tea leaves using UF-UPLC-Q/TOF-MS/MS and molecular docking

Published:2019 Issue:4 Volume:10 Page:1893-1902
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ning Zi-wan¹²³⁴^ORCID,Zhai Li-xiang¹²³⁴,Huang Tao¹²³⁴,Peng Jiao⁵⁶⁷⁸⁴,Hu Die⁵⁶⁷⁸⁴,Xiao Hai-tao⁵⁶⁷⁸⁴,Wen Bo¹²³⁴,Lin Cheng-yuan¹²³⁴,Zhao Ling¹²³⁴,Bian Zhao-xiang¹²³⁴

Affiliation:

1. School of Chinese Medicine

2. Hong Kong Baptist University

3. Kowloon

4. China

5. School of Pharmaceutical Sciences

6. Health Science Center

7. Shenzhen University

8. Shenzhen

Abstract

11 potential α-glucosidase inhibitors in leaves of Cyclocarya paliurus were quickly identified by UF-UPLC-Q/TOF-MS/MS, and their inhibitory activities were verified in vitro and in vivo, as well as docked with homology model.

Funder

Hong Kong Baptist University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C8FO01845F

Reference32 articles.

1. Human Proislet Peptide Promotes Pancreatic Progenitor Cells to Ameliorate Diabetes Through FOXO1/Menin-Mediated Epigenetic Regulation

2. Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase

3. A novel library of -arylketones as potential inhibitors of α-glucosidase: Their design, synthesis, in vitro and in vivo studies