HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay-Reference-Cited by-同舟云学术

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HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay

Published:2016 Issue:3 Volume:7 Page:2094-2099
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Hu Jun Jacob¹²³,Wong Nai-Kei¹²³,Lu Ming-Yang¹²³,Chen Xingmiao⁴²³,Ye Sen¹²³,Zhao Angela Qian¹²³,Gao Peng⁵⁶³,Yi-Tsun Kao Richard⁵⁶³,Shen Jiangang⁴²³,Yang Dan¹²³

Affiliation:

1. Morningside Laboratory for Chemical Biology and Department of Chemistry

2. The University of Hong Kong

3. P. R. China

4. School of Chinese Medicine

5. Department of Microbiology

6. Research Center of Infection and Immunology and State Key Laboratory of Emerging Infectious Diseases

Abstract

We describe an ultra-selective and ultra-sensitive HOCI fluorescent probe HKOCl-3 for live-cell and in vivo imaging and quantitative applications.

Funder

University of Hong Kong

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC03855C

Reference48 articles.

1. Reconciling the chemistry and biology of reactive oxygen species

2. Antimicrobial reactive oxygen and nitrogen species: concepts and controversies

3. The inhibition of bacterial growth by hypochlorous acid. Possible role in the bactericidal activity of phagocytes

4. Lethal Weapons

5. Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

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