Cholesterol inhibits oxygen permeation through biological membranes: mechanism against double-bond peroxidation

Author:

Boonnoy Phansiri12,Janlad Minchakarn12,Bagheri Behnaz34ORCID,Dias Cristiano5,Karttunen Mikko67ORCID,Wong-ekkabut Jirasak12ORCID

Affiliation:

1. Department of Physics, Faculty of Science, Kasetsart University, 50 Ngamwongwan Rd, Chatuchak, Bangkok, 10900, Thailand

2. Computational Biomodelling Laboratory for Agricultural Science and Technology (CBLAST), Faculty of Science, Kasetsart University, 50 Ngamwongwan Rd, Chatuchak, Bangkok, 10900, Thailand

3. Department of Applied Physics and Science Education, Technical University of Eindhoven, PO Box 513, 5600 MB, Eindhoven, The Netherlands

4. Institute for Complex Molecular Systems, PO Box 513, 5600 MB, Eindhoven, The Netherlands

5. Department of Physics, New Jersey Institute of Technology, Newark, New Jersey 07102-1982, USA

6. Department of Chemistry, Western University, 1151 Richmond Street, London, Ontario, N6A 5B7, Canada

7. Department of Physics and Astronomy, Western University, 1151 Richmond Street, London, Ontario, N6A 3K7, Canada

Abstract

Cholesterol decreases oxygen permeability across the unsaturated lipid bilayer.

Funder

National Research Council of Thailand

Kasetsart University Research and Development Institute

Natural Sciences and Engineering Research Council of Canada

Canada Research Chairs

Alliance de recherche numérique du Canada

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

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