Quantitative investigation of MDA-MB-231 breast cancer cell motility: dependence on epidermal growth factor concentration and its gradient
Author:
Affiliation:
1. The Gene and Linda Voiland School of Chemical Engineering and Bioengineering
2. Washington State University
3. Pullman
4. USA
Abstract
Analysis of the individually tracked cells showed that migration of MDA-MB-231 cells depends only on the ligand gradient. Only a small percentage of cells were responsive to the ligand stimulation, which highlighted the necessity of individual cell level studies to capture the biological reality.
Funder
Washington State University
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2017/MB/C7MB00390K
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