An aptamer-based chemiluminescence method for ultrasensitive detection of platelet-derived growth factor by cascade amplification combining rolling circle amplification with hydroxylamine-enlarged gold nanoparticles
Author:
Affiliation:
1. Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)
2. Tianjin 300072
3. PR China
4. School of Pharmaceutical Science and Technology
5. Tianjin University
Abstract
An ultrasensitive and selective chemiluminescence assay for PDGF-BB detection using the powerful signal amplification capability of RCA and hydroxylamine-amplified AuNPs.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/AY/C5AY01953B
Reference36 articles.
1. Platelets as a source of fibroblast growth-promoting activity
2. The PDGF family: four gene products form five dimeric isoforms
3. PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
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