Substrate-directed chemo- and regioselective synthesis of polyfunctionalized trifluoromethylarenes via organocatalytic benzannulation-Reference-Cited by-同舟云学术

Substrate-directed chemo- and regioselective synthesis of polyfunctionalized trifluoromethylarenes via organocatalytic benzannulation

Published:2020 Issue:3 Volume:7 Page:563-570
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Ji Yan-Ling¹²³⁴⁵,He Xiang-Hong¹²³⁴⁵^ORCID,Li Guo¹²³⁴⁵,Ai Yue-Yan¹²³⁴⁵,Li He-Ping¹²³⁴⁵,Peng Cheng¹²³⁴⁵^ORCID,Han Bo¹²³⁴⁵^ORCID

Affiliation:

1. Hospital of Chengdu University of Traditional Chinese Medicine

2. State Key Laboratory of Southwestern Chinese Medicine Resources

3. School of Pharmacy

4. Chengdu University of Traditional Chinese Medicine

5. Chengdu

Abstract

Highly chemo- and regioselective substrate-directed benzannulation of trisubstituted CF₃-alkenes and 2-benzylidenemalononitriles or 2-nitroallylic acetates has been achieved via Michael-initiated [4 + 2] or Rauhut–Currier-initiated [3 + 3] annulation.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Sichuan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01436E

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