Synthesis of 3,3-disubstituted-2,3-dihydroazanaphthoquinones via simultaneous alkyne oxidation and nitrile hydration of ortho-alkynylarenenitriles-Reference-Cited by-同舟云学术

Synthesis of 3,3-disubstituted-2,3-dihydroazanaphthoquinones via simultaneous alkyne oxidation and nitrile hydration of ortho-alkynylarenenitriles

Published:2014 Issue:33 Volume:12 Page:6440-6446
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Sakthivel Karuppusamy¹²³,Srinivasan Kannupal¹²³

Affiliation:

1. School of Chemistry

2. Bharathidasan University

3. Tiruchirappalli-620 024, India

Abstract

Simultaneous activation of alkynes and nitriles in o-alkynylarenenitriles in the presence of Pd(OAc)₂/H₂O/(±)-CSA afforded 3,3-disubstituted-2,3-dihydroazanaphthoquinones in moderate to excellent yields.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00852A

Reference48 articles.

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