Effects of (5′S)-5′,8-cyclo-2′-deoxyadenosine on the base excision repair of oxidatively generated clustered DNA damage. A biochemical and theoretical study-Reference-Cited by-同舟云学术

Effects of (5′S)-5′,8-cyclo-2′-deoxyadenosine on the base excision repair of oxidatively generated clustered DNA damage. A biochemical and theoretical study

Published:2014 Issue:43 Volume:12 Page:8671-8682
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Karwowski Boleslaw T.¹²³⁴⁵,Bellon Sophie⁶⁷⁸⁹,O'Neill Peter⁶⁷⁸⁹,Lomax Martine E.⁶⁷⁸⁹,Cadet Jean⁴⁵¹⁰¹¹⁵

Affiliation:

1. Food Science Department

2. Medical University of Lodz

3. 90-151 Lodz, Poland

4. CEA

5. INAC

6. MRC/CRUK Oxford Institute of Radiation Oncology

7. University of Oxford

8. Old Road Campus Research Building

9. Oxford, UK

10. F-38000 Grenoble, France

11. Univ. Grenoble Alpes

Abstract

Rejoining of an AP-site in ds-DNA containing the (5′S)-cdA in the complementary strand. Distance betwene AP-site and (5′S)-cdA, lanes: (1–6) −8 bases; (7–12) no (5′S)-cdA (control); (13–18) +8 bases.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01089B

Reference52 articles.

1. Processing of DNA damage clusters in human cells: current status of knowledge

2. Oxidatively generated complex DNA damage: Tandem and clustered lesions

3. Delayed repair of radiation induced clustered DNA damage: Friend or foe?

4. Induction and Repair of Clustered DNA Lesions: What Do We Know So Far?

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