Copper-catalyzed retro-aldol reaction of β-hydroxy ketones or nitriles with aldehydes: chemo- and stereoselective access to (E)-enones and (E)-acrylonitriles-Reference-Cited by-同舟云学术

Copper-catalyzed retro-aldol reaction of β-hydroxy ketones or nitriles with aldehydes: chemo- and stereoselective access to (E)-enones and (E)-acrylonitriles

Published:2016 Issue:30 Volume:14 Page:7282-7294
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Song-Lin¹²³⁴⁵,Deng Zhu-Qin¹²³⁴⁵

Affiliation:

1. The Key Laboratory of Food Colloids and Biotechnology

2. Ministry of Education

3. School of Chemical and Material Engineering

4. Jiangnan University

5. Wuxi 214122

Abstract

A mild and efficient copper-catalyzed retro-aldol reaction of β-hydroxy ketones or nitriles with benzaldehydes produces chemo-, regio- and stereoselectively (E)-enones and (E)-acrylonitriles.

Funder

National Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01198E

Reference64 articles.

1. Chiral Bis(oxazoline) Copper(II) Complexes: Versatile Catalysts for Enantioselective Cycloaddition, Aldol, Michael, and Carbonyl Ene Reactions

2. Asymmetric Catalysis of Aldol Reactions with Chiral Lewis Bases