A novel lurasidone hydrochloride–shikimic acid co-amorphous system formed by hydrogen-bonding interaction with the retained pH-dependent solubility behavior-Reference-Cited by-同舟云学术

A novel lurasidone hydrochloride–shikimic acid co-amorphous system formed by hydrogen-bonding interaction with the retained pH-dependent solubility behavior

Published:2020 Issue:35 Volume:22 Page:5841-5853
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Hu Yi¹²³⁴,Jiang Cuiping⁵⁶⁷⁴,Li Bin¹²³⁴,Zhou Lijing¹²³⁴,Xu Renjie¹²³⁴,Guo Yujie¹²³⁴,Cao Yan¹²³⁴,Cao Guosheng¹²³⁴,Lu Shan¹²³⁴^ORCID

Affiliation:

1. School of Pharmacy

2. Hubei University of Chinese Medicine

3. Wuhan 430065

4. PR China

5. School of Traditional Chinese Medicine

6. Southern Medical University

7. Guangzhou 510515

Abstract

The current study was aimed at investigating the lurasidone hydrochloride–shikimic acid co-amorphous system using a new type of organic acid.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CE/D0CE00952K

Reference50 articles.

1. Pharmacological Profile of Lurasidone, a Novel Antipsychotic Agent with Potent 5-Hydroxytryptamine 7 (5-HT7) and 5-HT1A Receptor Activity

2. Coamorphous Lurasidone Hydrochloride–Saccharin with Charge-Assisted Hydrogen Bonding Interaction Shows Improved Physical Stability and Enhanced Dissolution with pH-Independent Solubility Behavior

3. Pharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats

4. Solution and calorimetric thermodynamic study of a new 1 : 1 sulfamethazine–3-methylsalicylic acid co-crystal

5. 4-Aminoquinaldine monohydrate polymorphism: prediction and impurity aided discovery of a difficult to access stable form

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