Two methods for the preparation of sitagliptin phosphate via chemical resolution and asymmetric hydrogenation
Author:
Affiliation:
1. School of Chemistry and Chemical Engineering
2. Ningxia Normal University
3. Guyuan
4. China
Abstract
Two effective processes have been developed for the preparation of sitagliptin phosphate.
Funder
Natural Science Foundation of Ningxia Province
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA10273C
Reference34 articles.
1. Discovery of JANUVIA™ (Sitagliptin), a Selective Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type2 Diabetes.
2. Inhibition of Dipeptidyl Peptidase-4 Reduces Glycemia, Sustains Insulin Levels, and Reduces Glucagon Levels in Type 2 Diabetes
3. International Diabetes Federation (IDF) , Diabetes Atlas , 2019 , 9th edn, http://www.idf.org/diabetesatlas
4. www.diabetes.org
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