Regulation of the innate immune system by fragmented heparin-conjugated lipids on lipid bilayered membranes <i>in vitro</i>-Reference-Cited by-同舟云学术

Regulation of the innate immune system by fragmented heparin-conjugated lipids on lipid bilayered membranes in vitro

Published:2023 Issue:46 Volume:11 Page:11121-11134
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Adler Anna¹^ORCID,Fritsch Marlene¹,Fromell Karin¹,Leneweit Gero²³^ORCID,Ekdahl Kristina N.¹⁴,Nilsson Bo¹,Teramura Yuji¹⁵⁶^ORCID

Affiliation:

1. Department of Immunology, Genetics and Pathology (IGP), Uppsala University, Dag Hammarskjölds väg 20, SE-751 85, Uppsala, Sweden

2. ABNOBA GmbH, Pforzheim, Germany

3. Carl Gustav Carus-Institute, Association for the Promotion of Cancer Therapy, Niefern-Öschelbronn, Germany

4. Linnaeus Center of Biomaterials Chemistry, Linnaeus University, SE-391 82 Kalmar, Sweden

5. Cellular and Molecular Biotechnology Research Institute (CMB), National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central Fifth, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan

6. Master's/Doctoral Program in Life Science Innovation (T-LSI), University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577, Japan

Abstract

Surface modification with heparin is a powerful biomaterial coating strategy that protects against innate immunity activation since heparin is a part of the proteoglycan heparan sulfate on cell surfaces in the body.

Funder

Japan Society for the Promotion of Science

Vetenskapsrådet

Ministry of Education, Culture, Sports, Science and Technology

Horizon 2020

Bundesministerium für Bildung und Forschung

VINNOVA

Bpifrance

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine