Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin-Reference-Cited by-同舟云学术

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Mechanisms of cell uptake and toxicity of the anticancer drug cisplatin

Published:2014 Issue:11 Volume:6 Page:2126-2133
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Eljack Nasma D.¹²³,Ma Ho-Yu M.¹²³,Drucker Janine⁴⁵,Shen Clara¹²³,Hambley Trevor W.¹²³,New Elizabeth J.¹²³,Friedrich Thomas⁴⁵,Clarke Ronald J.¹²³

Affiliation:

1. School of Chemistry

2. University of Sydney

3. , Australia

4. Institute of Chemistry

5. , Germany

Abstract

Cisplatin is capable of passively diffusing across a lipid bilayer and has no absolute requirement for any protein-mediated uptake mechanism.

Funder

National Health and Medical Research Council

Deutsche Forschungsgemeinschaft

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MT/C4MT00238E

Reference36 articles.

1. Platinum binding to DNA: structural controls and consequences

2. Cisplatin: a review of toxicities and therapeutic applications

3. Resistance to platinum compounds: Mechanisms and beyond

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