Synthesis, screening and biological activity of potent thiosemicarbazone compounds as a tyrosinase inhibitor-Reference-Cited by-同舟云学术

Synthesis, screening and biological activity of potent thiosemicarbazone compounds as a tyrosinase inhibitor

Published:2019 Issue:35 Volume:43 Page:14102-14111
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Cai Penggen¹²³⁴,Xiong Yi¹²³⁴^ORCID,Yao Yao¹²³⁴,Chen Wu¹²³⁴,Dong Xiongwei¹²³⁴^ORCID

Affiliation:

1. National Local Joint Engineering Laboratory for Advanced Textile Processing and Clean Production

2. Wuhan Textile University

3. Wuhan 430200

4. China

Abstract

Inhibitors are designed based on coordination chemistry and catalytic circle of the tyrosinase, coordination atoms binds to copper and blocks enzyme activity, indicated that thiosemicarbazone species possess good potential as tyrosinase inhibitors.

Funder

Natural Science Foundation of Hubei Province

National Natural Science Foundation of China

Hubei Provincial Department of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ02360G

Reference43 articles.

1. Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors

2. Thiosemicarbazones as inhibitors of tyrosinase enzyme

3. Antibacterial, antifungal and in vitro antileukaemia activity of metal complexes with thiosemicarbazones

4. The rational design of specific SOD1 inhibitors via copper coordination and their application in ROS signaling research

5. Nickel (II) complexes of naphthaquinone thiosemicarbazone and semicarbazone: Synthesis, structure, spectroscopy, and biological activity

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