Pd(<scp>ii</scp>)-catalyzed annulation of terminal alkynes with 2-pyridinyl-substituted <i>p</i>-quinone methides: direct access to indolizines-Reference-Cited by-同舟云学术

Pd(ii)-catalyzed annulation of terminal alkynes with 2-pyridinyl-substituted p-quinone methides: direct access to indolizines

Published:2022 Issue:95 Volume:58 Page:13238-13241
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Ahmad Feroz¹,Ranga Pavit K.¹,Pankhade Yogesh A.¹,Fatma Shaheen¹,Gouda Ashrumochan¹,Anand Ramasamy Vijaya¹^ORCID

Affiliation:

1. Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali, Sector 81, Knowledge City, S. A. S. Nagar, Manauli (PO), Punjab, 140306, India

Abstract

A Pd-catalysed 100% atom-economical method has been developed for the synthesis of 1,3-disubstituted indolizine derivatives in good yields through a regiospecific formal [3 + 2]-annulation from 2-pyridinyl-substituted p-quinone methides and terminal alkynes.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC04395E

Reference47 articles.

1. Synthesis and Biological Activity of Lamellarin Alkaloids: An Overview

2. Indolizidine and quinolizidine alkaloids

3. Anticancer Properties of Lamellarins

4. Herbicidal indolizine-5,8-diones: photosystem I redox mediators

5. Indolizine-Based Scaffolds as Efficient and Versatile Tools: Application to the Synthesis of Biotin-Tagged Antiangiogenic Drugs

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