Development of a new heparan sulfate proteoglycan (HSPG) chromolith LC column to study the pH dependence binding of peptide vaccines to HSPG and role of human serum albumin on its binding-Reference-Cited by-同舟云学术

Development of a new heparan sulfate proteoglycan (HSPG) chromolith LC column to study the pH dependence binding of peptide vaccines to HSPG and role of human serum albumin on its binding

Published:2023 Issue:10 Volume:15 Page:1323-1335
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

André Claire¹^ORCID,Lethier Lydie¹,Adotevi Olivier²,Guillaume Yves Claude¹³^ORCID

Affiliation:

1. Pôle Chimie Analytique Bioanalytique et Physique (PCABP), EA 481 Neurosciences Intégrative et Cliniques, Univ. Bourgogne Franche-Comté, Besançon, F-2500, France

2. Univ. Bourgogne Franche Comté, INSERM, EFS BFC, UMR 1098, RIGHT Interactions Greffon-Hôte Tumeur/Ingénierie Cellulaire et Génique, Besançon, F-2500, France

3. Pôle Pharmaceutique, University Hospital of Besançon, Besançon, F-2500, France

Abstract

Heparan sulfate proteoglycan (HSPG) expressed on immune cell surface participate in antitumor T-cell responses generated in the acidic lymph node (LN) microenvironment.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AY/D3AY00046J

Reference37 articles.

1. Universal tumor-reactive helper peptides from telomerase as new tools for anticancer vaccination

2. A Phase II Study Evaluating the Interest to Combine UCPVax, a Telomerase CD4 TH1-Inducer Cancer Vaccine, and Atezolizumab for the Treatment of HPV Positive Cancers: VolATIL Study

3. Lymph Nodes as Anti-Tumor Immunotherapeutic Tools: Intranodal-Tumor-Specific Antigen-Pulsed Dendritic Cell Vaccine Immunotherapy

4. T-cells produce acidic niches in lymph nodes to suppress their own effector functions

5. Degradation studies of levosimendan isolation, identification, and structure confirmation of stress degradation products using LCMS, mass mediated Prep-HPLC, NMR, HRMS, SFC and FTIR