The preventive effect of linalool on acute and chronic UVB-mediated skin carcinogenesis in Swiss albino mice-Reference-Cited by-同舟云学术

The preventive effect of linalool on acute and chronic UVB-mediated skin carcinogenesis in Swiss albino mice

Published:2016 Issue:7 Volume:15 Page:851-860
ISSN:1474-905X
Container-title:Photochemical & Photobiological Sciences
language:en
Short-container-title:Photochem. Photobiol. Sci.

Author:

Gunaseelan Srithar¹²³⁴,Balupillai Agilan¹²³⁴,Govindasamy Kanimozhi¹²³⁴,Muthusamy Ganesan¹²³⁴,Ramasamy Karthikeyan¹²³⁴,Shanmugam Mohana¹²³⁴,Prasad N. Rajendra¹²³⁴

Affiliation:

1. Department of Biochemistry and Biotechnology

2. Annamalai University

3. Annamalainagar-608 002

4. India

Abstract

Acute UVB-exposure induces erythema and edema. Repeated UVB-exposure causes chronic inflammation and mutated p53 expression which leads to carcinogenesis. Linalool through its (i) sunscreen effect, (ii) modulation of NF-κB signaling and (iii) apoptotic signaling prevents photocarcinogenesis.

Funder

University Grants Commission

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/PP/C6PP00075D

Reference39 articles.

1. Modulation of UVB-induced Oxidative Stress by Ursolic Acid in Human Blood Lymphocytes

2. Dietary Grape Seed Proanthocyanidins Inhibit UVB-Induced Cyclooxygenase-2 Expression and Other Inflammatory Mediators in UVB-Exposed Skin and Skin Tumors of SKH-1 Hairless Mice

3. Docosahexaenoic Acid Inhibits UVB-Induced Activation of NF-κB and Expression of COX-2 and NOX-4 in HR-1 Hairless Mouse Skin by Blocking MSK1 Signaling

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