Cocrystals of zileuton with enhanced physical stability
Author:
Affiliation:
1. Laboratory of Magnetic Resonance Spectroscopy and Imaging
2. Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences
3. Suzhou 215123
4. P.R. China
5. School of Pharmacy
6. Crystal Pharmatech
Abstract
Zileuton can form two promising pharmaceutical cocrystals with nicotinamide and isonicotinamide, which demonstrate superior phase stability against moisture.
Funder
National Natural Science Foundation of China
Youth Innovation Promotion Association of the Chinese Academy of Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CE/C7CE02150J
Reference40 articles.
1. Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?
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4. The Effects of a 5-Lipoxygenase Inhibitor on Asthma Induced by Cold, Dry Air
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