1. School of Natural and Environmental Sciences - Chemistry, Newcastle University, Newcastle, NE1 7RU, UK
2. Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK
3. Radcliffe Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Roosevelt Drive, Old Road Campus, Oxford, OX3 7BN, UK
4. Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford OX3 7FZ, UK
5. Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK
6. Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, CB4 0WG, UK
7. Emerging Innovations Unit, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK