Glutaredoxin1 knockout promotes high-fat diet-induced obesity in male mice but not in female ones-Reference-Cited by-同舟云学术

Glutaredoxin1 knockout promotes high-fat diet-induced obesity in male mice but not in female ones

Published:2021 Issue:16 Volume:12 Page:7415-7427
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zou Xiaoyu¹,Ahmad Muhammad Ijaz¹,Zhao Di¹,Zhang Min¹,Li Chunbao¹²³^ORCID

Affiliation:

1. Jiangsu Collaborative Innovation Center of Meat Production and Processing, Quality and Safety Control; Key Laboratory of Meat Processing and Quality Control, MOE; Key Laboratory of Meat Products Processing, MOA; Nanjing Agricultural University, Nanjing 210095, P.R. China

2. Joint International Research Laboratory of Animal Health and Food Safety, MOE, Nanjing Agricultural University, Nanjing 210095, P.R. China

3. National Center for International Research on Animal Gut Nutrition, Nanjing Agricultural University, Nanjing 210095, P.R. China

Abstract

Glrx1 deficiency aggravated high-fat-diet-induced hyperlipidemia, liver injury and oxidative stress. Diet altered the gut microbiota composition. The results provide a new insight into the susceptibilities to obesity between males and females.

Funder

National Natural Science Foundation of China

Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO01241J

Reference53 articles.

1. Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations

2. Processed Meat Protein Promoted Inflammation and Hepatic Lipogenesis by Upregulating Nrf2/Keap1 Signaling Pathway in Glrx-Deficient Mice