Efficient synthesis of 4-sulfanylcoumarins from 3-bromo-coumarins via a highly selective DABCO-mediated one-pot thia-Michael addition/elimination process-Reference-Cited by-同舟云学术

Efficient synthesis of 4-sulfanylcoumarins from 3-bromo-coumarins via a highly selective DABCO-mediated one-pot thia-Michael addition/elimination process

Published:2020 Issue:1 Volume:10 Page:482-491
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Mostardeiro Vitor B.¹²³⁴,Dilelio Marina C.¹²³⁴,Kaufman Teodoro S.⁵⁶⁷^ORCID,Silveira Claudio C.¹²³⁴^ORCID

Affiliation:

1. Departamento de Química

2. Universidade Federal de Santa Maria

3. Santa Maria

4. Brazil

5. Instituto de Química Rosario (IQUIR, CONICET-UNR)

6. 2000 Rosario

7. Argentina

Abstract

A facile, simple and metal-free protocol for the 4-sulfanylation of 3-bromocoumarins was developed. It involves a thia-Michael addition and a dehydrobromination under DABCO assistance.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Consejo Nacional de Investigaciones Científicas y Técnicas

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/C9RA09545D

Reference83 articles.

1. The Structure and Pharmacological Functions of Coumarins and Their Derivatives