Imidazole synthesis by transition metal free, base-mediated deaminative coupling of benzylamines and nitriles-Reference-Cited by-同舟云学术

Imidazole synthesis by transition metal free, base-mediated deaminative coupling of benzylamines and nitriles

Published:2017 Issue:98 Volume:53 Page:13133-13136
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Das Uttam Kumar¹²³,Shimon Linda J. W.⁴²³,Milstein David¹²³^ORCID

Affiliation:

1. Department of Organic Chemistry, Weizmann Institute of Science

2. Rehovot 76100

3. Israel

4. Department of Chemical Research Support, Weizmann Institute of Science

Abstract

An unprecedented transition metal free, base-mediated deaminative coupling of benzylamines and nitriles is reported. This protocol provides a practical strategy for the synthesis of 2,4,5-tri-substituted imidazoles with liberation of NH₃.

Funder

European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CC/C7CC08322J

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