Computational approach: 3D-QSAR, molecular docking, ADMET, molecular dynamics simulation investigations, and retrosynthesis of some curcumin analogues as PARP-1 inhibitors targeting colon cancer-Reference-Cited by-同舟云学术

Computational approach: 3D-QSAR, molecular docking, ADMET, molecular dynamics simulation investigations, and retrosynthesis of some curcumin analogues as PARP-1 inhibitors targeting colon cancer

Published:2023 Issue:45 Volume:47 Page:20987-21009
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Zrinej Jamal¹^ORCID,Elmchichi Larbi¹^ORCID,Alaqarbeh Marwa²^ORCID,Lakhlifi Tahar¹,Bouachrine Mohammed¹³

Affiliation:

1. Molecular Chemistry and Natural Substances Laboratory, Department of Chemistry, Faculty of Science, University of Moulay Ismail, Meknes, Morocco

2. Basic Science Department, Prince Al Hussein bin Abdullah II Academy for Civil Protection, Al-Balqa Applied University, Al-Salt 19117, Jordan

3. EST Khenifra, Sultan Moulay Slimane University, Beni Mellal, Morocco

Abstract

As cancer is the second-leading cause of death globally, this study strives to find efficient medications for colon cancer that cause minimal side effects.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ03981A

Reference84 articles.

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2. Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer

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