piRNAs in the human retina and retinal pigment epithelium reveal a potential role in intracellular trafficking and oxidative stress-Reference-Cited by-同舟云学术

piRNAs in the human retina and retinal pigment epithelium reveal a potential role in intracellular trafficking and oxidative stress

Published:2024 Issue:4 Volume:20 Page:248-264
ISSN:2515-4184
Container-title:Molecular Omics
language:en
Short-container-title:Mol. Omics

Author:

Karpagavalli Muthuramalingam¹,Sivagurunathan Suganya²,Panda T. Sayamsmruti³,Srikakulam Nagesh⁴,Arora Reety⁵,Dohadwala Lamiya⁵,Tiwary Basant K.³,Sadras Sudha Rani¹,Arunachalam Jayamuruga Pandian⁶,Pandi Gopal⁴,Chidambaram Subbulakshmi¹^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, Pondicherry University, Puducherry-605014, India

2. RS Mehta Jain Department of Biochemistry and Cell Biology, Vision Research Foundation, Chennai, India

3. Department of Bioinformatics, Pondicherry University, Puducherry-605014, India

4. Laboratory of RNA Biology and Epigenomics, Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai, India

5. National Centre for Biological Sciences, TIFR, Bangalore, India

6. Central Inter-Disciplinary Research Facility, Sri Balaji Vidyapeeth (Deemed to be University), Pondicherry-607402, India

Abstract

piRNAs profiled from human retina/RPE share seed sequence homology with miRNAs and lncRNAs. They play regulatory roles in intracellular transport, circadian rhythm, oxidative stress, and retinal neurodegeneration.

Funder

Science and Engineering Research Board

Indian Council of Medical Research

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MO/D3MO00122A

Reference94 articles.

1. A novel class of small RNAs bind to MILI protein in mouse testes

2. Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

3. A novel class of small RNAs in mouse spermatogenic cells

4. The Biogenesis and Function of PIWI Proteins and piRNAs: Progress and Prospect

5. piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development