Microfluidics for single-cell genetic analysis
Author:
Affiliation:
1. Department of Chemistry
2. University of Washington
3. Seattle, USA
4. Clinical Research Division
5. Fred Hutchinson Cancer Research Center
Abstract
New tools are needed to study single-cell genetics, and a microfluidic approach offers unique advantages and challenges.
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2014/LC/C4LC00175C
Reference36 articles.
1. Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments
2. A Comprehensive Survey of Clonal Diversity Measures in Barrett's Esophagus as Biomarkers of Progression to Esophageal Adenocarcinoma
3. Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype
4. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
5. Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
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