Anti-osteosarcoma effect of hydroxyapatite nanoparticles both in vitro and in vivo by downregulating the FAK/PI3K/Akt signaling pathway

Author:

Wang Renxian12345ORCID,Liu WeiFeng64758,Wang Qian12345,Li Guangping12345,Wan Ben12345,Sun Yuyang12345,Niu Xiaohui64758,Chen Dafu12345,Tian Wei941058

Affiliation:

1. Laboratory of Bone Tissue Engineering

2. Beijing Laboratory of Biomedical Materials

3. Beijing Research Institute of Traumatology and Orthopaedics

4. Beijing Jishuitan Hospital

5. Beijing 100035

6. Depatment of Orthopaedic Oncology Surgery

7. Peking Universit

8. China

9. Department of Spine Surgery

10. Peking University

Abstract

Schematic representing the anti-cancer effects of nano-HAPs both in vitro and in vivo by downregulating the FAK/PI3K/Akt signaling pathway.

Funder

Natural Science Foundation of Beijing Municipality

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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