Click and count: specific detection of acid ceramidase activity in live cells-Reference-Cited by-同舟云学术

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Click and count: specific detection of acid ceramidase activity in live cells

Published:2020 Issue:48 Volume:11 Page:13044-13051
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Casasampere Mireia¹²³⁴⁵,Izquierdo Eduardo¹²³⁴⁵,Casas Josefina¹²³⁴⁵,Abad José Luís¹²³⁴⁵,Liu Xiao⁶⁷⁸⁹^ORCID,Xu Ruijuan¹⁰¹¹¹²,Mao Cungui¹⁰¹¹¹²,Chang Young-Tae⁶⁷⁸⁹¹³^ORCID,Delgado Antonio¹²³⁴⁵^ORCID,Fabrias Gemma¹²³⁴⁵^ORCID

Affiliation:

1. Research Unit on BioActive Molecules

2. Department of Biological Chemistry

3. Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

4. 08034-Barcelona

5. Spain

6. Department of Chemistry

7. Pohang University of Science and Technology (POSTECH)

8. Pohang

9. Korea

10. Department of Medicine and Cancer Center

11. The State University of New York at Stony Brook

12. USA

13. Center for Self-assembly and Complexity

Abstract

The use of intact cells in medical research offers a number of advantages over employing cell-free systems.

Funder

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03166F

Reference37 articles.

1. Ceramidases in Hematological Malignancies: Senseless or Neglected Target?

2. Ceramidases, roles in sphingolipid metabolism and in health and disease

3. Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells

4. Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells

5. Acid Ceramidase in Melanoma

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1. A fluorogenic substrate for the detection of lipid amidases in intact cells;Journal of Lipid Research;2024-03

2. Live‐Cell‐Selective Probes;Sensors and Probes for Bioimaging;2023-06-02

3. Quantitative Structure-Activity Relationship of Fluorescent Probes and Their Intracellular Localizations;Chemosensors;2023-05-22

4. High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase;Journal of Enzyme Inhibition and Medicinal Chemistry;2022-12-15

5. Fluorescently Labeled Ceramides and 1-Deoxyceramides: Synthesis, Characterization, and Cellular Distribution Studies;The Journal of Organic Chemistry;2022-11-28

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