p,p′-Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways

Author:

Song Li12345,Zhao Meirong6785,Liu Jianxin12345,Li Zhuoyu12345,Xiao Hong91011125,Liu Weiping131415165

Affiliation:

1. Institute of Biotechnology

2. Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education

3. Shanxi University

4. Taiyuan 030006

5. China

6. Research Center of Environmental Science

7. Zhejiang University of Technology

8. Hangzhou 310032

9. Department of Pathology

10. The First Affiliated Hospital

11. Shanxi Medical University

12. Taiyuan

13. MOE Key Lab of Environmental Remediation and Ecosystem Health

14. College of Environmental and Resource Sciences

15. Zhejiang University

16. Hangzhou 310058

Abstract

p,p′-Dichlorodiphenyltrichloroethane is able to inhibit the apoptosis of human colorectal adenocarcinoma cells, which may be an important mechanism to contribute to colorectal cancer development.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

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