The induction of apoptosis in BEL-7402 cells through the ROS-mediated mitochondrial pathway by a ruthenium(ii) polypyridyl complex-Reference-Cited by-同舟云学术

The induction of apoptosis in BEL-7402 cells through the ROS-mediated mitochondrial pathway by a ruthenium(ii) polypyridyl complex

Published:2014 Issue:6 Volume:38 Page:2554-2563
ISSN:1144-0546
Container-title:New J. Chem.
language:en
Short-container-title:New J. Chem.

Author:

Jiang Guang-Bin¹²³,Yao Jun-Hua⁴⁵³,Wang Ji¹²³,Li Wei¹²³,Han Bing-Jie¹²³,Xie Yang-Yin¹²³,Lin Gan-Jian¹²³,Huang Hong-Liang⁶²³,Liu Yun-Jun¹²³

Affiliation:

1. School of Pharmacy

2. Guangdong Pharmaceutical University

3. Guangzhou, PR China

4. Instrumentation Analysis and Research Center

5. Sun Yat-Sen University

6. School of Life Science and Biopharmaceutical

Abstract

The in vitro cytotoxicity, apoptosis, cellular uptake, cell cycle arrest, ROS, mitochondrial membrane potential, western blot analysis and DNA-binding induced by Ru1 were investigated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/NJ/C3NJ01467C

Reference47 articles.

1. Polypyridyl Metal Complexes with Biological Activity

2. Recent Developments in the Field of Tumor-Inhibiting Metal Complexes

3. Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

4. New [Ru(5,6-dmp/3,4,7,8-tmp)2(diimine)]2+ complexes: Non-covalent DNA and protein binding, anticancer activity and fluorescent probes for nuclear and protein components

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