Complementary oligonucleotides regulate induced fit ligand binding in duplexed aptamers
Author:
Affiliation:
1. McGill University and Genome Quebec Innovation Centre
2. Montreal
3. Canada
4. Department of Biomedical Engineering
5. McGill University
Abstract
Hybridizing a complementary oligonucleotide to an ATP aptamer is shown to functionally regulate a newly revealed induced fit ligand-binding pathway.
Funder
Natural Sciences and Engineering Research Council of Canada
Canada Research Chairs
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC03993F
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