Protective activities of polysaccharides from Cipangopaludina chinensis against high-fat-diet-induced atherosclerosis via regulating gut microbiota in ApoE-deficient mice

Author:

Xiong Qingping12345,Zhu Lijun67894,Zhang Fengmin1011124,Li Hailun1314154,Wu Jun67894,Liang Jian67894,Yuan Jun1234,Shi Yingying12345,Zhang Qianghua12345,Hu Youdong123413ORCID

Affiliation:

1. Jiangsu Key Laboratory of Regional Resource Exploitation and Medicinal Research

2. Huaiyin Institute of Technology

3. Huai'an 223003

4. China

5. National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization

6. School of Pharmaceutical Sciences

7. Guangzhou University of Chinese Medicine

8. Guangzhou

9. 510006

10. Testing Center

11. Yangzhou University

12. Yangzhou 225009

13. Department of Geriatric Medicine

14. Affiliated Huai'an Hospital of Xuzhou Medical University

15. Huai'an 223002

Abstract

The supplementation of sulfated polysaccharides extracted from C. chinensis slows down the development of atherosclerosis caused by high-fat-diet-induced AS via regulating gut microbiota.

Funder

National Natural Science Foundation of China

Six Talent Peaks Project in Jiangsu Province

Huai’an Municipal Science and Technology Bureau

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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